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Adjective significant has 4 senses
significant, important - important in effect or meaning; "a significant change in tax laws"; "a significant change in the Constitution"; "a significant contribution"; "significant details"; "statistically significant"Antonyms:  insignificant, unimportant, hole-and-corner, hole-in-corner, inappreciable, light, superficial, trivial
 
significant, substantial - fairly large; "won by a substantial margin"Antonym:  inconsiderable (indirect, via considerable)
 
significant - too closely correlated to be attributed to chance and therefore indicating a systematic relation; "the interaction effect is significant at the .01 level"; "no significant difference was found"Antonym:  nonsignificant
 
meaning, pregnant, significant - rich in significance or implication; "a meaning look"; "pregnant with meaning"Antonyms:  meaningless, nonmeaningful (indirect, via meaningful)
 
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