Adverbial irregardless has 1 sense

1. irregardless - regardless; a combination of irrespective and regardless sometimes used humorously
   

Irregardless

Part of speech: Adverb

Definition: Regardless; in spite of everything; used to introduce a statement that is contrary to a previous statement.

Example sentences:

• Irregardless of the rain, he still went for a run.
• I know you advised against it, but irregardless, I decided to take the job offer.

Part of speech: Adjective (informal, nonstandard)

Definition: Without regard or consideration; disregarding.

Example sentences:

• He made an irregardless comment about her appearance, which offended her.
• Irregardless of the rules, she chose to follow her own path.