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splenetic
Adjectivesplenetic has 2 senses
splenic, splenetic, lienal - of or relating to the spleen
bristly, prickly, splenetic, waspish - very irritable; "bristly exchanges between the White House and the press"; "he became prickly and spiteful"; "witty and waspish about his colleagues" Antonym:good-natured (indirect, via ill-natured)