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Definitions from the Web

Pegolated

Description

Pegolated is an adjective that refers to a substance or compound that has been modified or coated with polyethylene glycol (PEG). This process helps improve various properties of the substance, such as solubility, stability, and biocompatibility.

Senses and Usages

1. Pharmaceutical Sense:

In the field of pharmaceuticals, pegolated substances are commonly used to enhance drug delivery systems. By pegolating certain drugs, their absorption rates can be improved, leading to more effective and targeted treatments.

Example Sentence: The pegolated insulin showed significantly better results in lowering blood sugar levels compared to the non-pegolated version.

2. Chemical Sense:

In chemistry, pegolation involves attaching PEG chains to molecules or compounds, providing various advantages such as increased water solubility and reduced immunogenicity.

Example Sentence: The pegolated nanoparticles displayed improved stability, making them highly suitable for biomedical applications.

3. Biotechnology Sense:

Biotechnologists often pegolate enzymes or proteins to enhance their stability, prolong their activity, or modify their behavior in biological systems.

Example Sentence: The pegolated antibodies exhibited a prolonged half-life, making them an ideal therapeutic option for chronic diseases.

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