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Definitions from WordNet

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Osteolysis

Osteolysis is the process of bone tissue degradation or destruction. It occurs when the normal balance between bone resorption and formation is disrupted, leading to net bone loss. Osteolysis can be caused by various factors, including diseases, infections, trauma, or medications.

Senses and Usages:

Noun:

• The pathological breakdown or loss of bone tissue.
• The localized dissolution and absorption of bone tissue.

Verb:

• To undergo or cause the breakdown or loss of bone tissue.
• To cause the localized dissolution and absorption of bone tissue.

Examples:

Noun:

1. The patient's X-ray revealed a significant osteolysis, indicative of bone damage.
2. The surgeon noted the presence of osteolysis during the operation.

Verb:

1. Long-term use of certain medications can lead to osteolysis and subsequent bone thinning.
2. High-impact sports can cause repeated stress on the joints, eventually leading to osteolysis.

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