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WordNet-Online
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Adjective loathsome has 2 senses
- nauseating, nauseous, noisome, loathsome, offensive, sickening, vile - causing or able to cause nausea; "a nauseating smell"; "nauseous offal"; "a sickening stench"
Antonym: wholesome (indirect, via unwholesome)
- disgusting, disgustful, distasteful, foul, loathly, loathsome, repellent, repellant, repelling, revolting, skanky, wicked, yucky - highly offensive; arousing aversion or disgust; "a disgusting smell"; "distasteful language"; "a loathsome disease"; "the idea of eating meat is repellent to me"; "revolting food"; "a wicked stench"
Antonym: inoffensive (indirect, via offensive)
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