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glucuronidation

 

Definitions from the Web

Term: Glucuronidation

Description:

Glucuronidation, in biochemistry, refers to the process of conjugation where glucuronic acid is attached to a substrate or drug molecule. This biotransformation reaction facilitates the excretion of various endogenous and exogenous compounds in the body. Glucuronidation is predominantly carried out in the liver.

Sample Sentences:

  1. The glucuronidation of the drug helps in its elimination from the body.
  2. Glucuronidation is an essential metabolic pathway involved in the detoxification of many xenobiotics.
  3. Impaired glucuronidation can lead to prolonged drug action and increased toxicity.

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