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Term: Acetyl group
Definition: The acetyl group is a chemical functional group consisting of a methyl group (CH3) bound to a carbonyl group. It is commonly symbolized as -COCH3 or -C(O)CH3 in chemical structures. It is derived from acetic acid and is present in various organic compounds.
Senses and Usages:
- Chemistry:
- As a functional group, the acetyl group is widely used in organic synthesis to modify and create new compounds.
- The acetyl group acts as an acylating agent, contributing to the acetylation of proteins and other molecules.
- Biochemistry:
- In biochemistry, the acetyl group is a crucial component of acetyl-CoA, an important molecule in metabolism.
- It participates in numerous biochemical reactions, such as the Krebs cycle and fatty acid synthesis.
- Pharmacology:
- Pharmaceuticals may contain acetyl groups as part of their chemical structure, conferring specific properties or functionality.
- Some drugs use acetyl groups to enhance drug delivery, stability, or efficacy.
- Medicine:
- In medicine, acetyl groups are relevant in the context of acetylation reactions involved in gene regulation and histone modification.
- Alterations in acetylation patterns have been linked to various diseases and conditions.
- Industrial Applications:
- The acetyl group finds use in various industrial processes, including the production of solvents, plastics, textiles, and pharmaceuticals.
- A variety of chemical reactions, such as acetylation and acetylene chemistry, rely on the acetyl group.
Sample Sentences:
- The compound undergoes transformation by the addition of an acetyl group.
- Acetylation of the protein was achieved by introducing an acetyl group to the amino acid residues.
- Acetyl-CoA plays a central role in energy production and metabolism.
- The drug's improved stability is attributed to the acetyl group present in its chemical structure.
- Studies suggest a correlation between histone acetylation and gene expression.
- The textile industry heavily relies on processes involving the acetyl group for colorfastness and dye fixation.
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